| The Breaker Lab

The Breaker Lab

M. G. Mohsen, Midy, M. K., Balaji, A., and Breaker, R. R., “Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches”, ACS Chem. Biol., 2024.

M. G. Mohsen, Midy, M. K., Balaji, A., and Breaker, R. R., “Exploiting natural riboswitches for aptamer engineering and validation”, Nucleic Acids Res., vol. 51, pp. 966–981, 2023.

H. Sadeeshkumar, Balaji, A., Sutherland, A. G., Mootien, S., Anthony, K. G., and Breaker, R. R., “Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch”, Anal. Biochem, 2023.

H. Salvail, Balaji, A., Roth, A., and Breaker, R. R., “A spermidine riboswitch class in bacteria exploits a close variant of an aptamer for the enzyme cofactor S-adenosylmethionine”, Cell Reports, vol. 42, 2023.

H. Salvail, Balaji, A., Yu, D., Roth, A., and Breaker, R., “Biochemical Validation of a Fourth Guanidine Riboswitch Class in Bacteria”, Biochemistry, 2020.