2023

R. R. Breaker, Harris, K. A., Lyon, S. E., Wencker, F. D. R., and Fernando, C. M., “Evidence that OLE RNA is a component of a major stress-responsive ribonucleoprotein particle in extremophilic bacteria”, Mol. Microbiol., 2023. [Link]
M. G. Mohsen and Breaker, R. R., “In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers”, Bio-protocol, vol. 13, 2023. [Link]
H. Salvail and Breaker, R. R., “Riboswitches”, Curr Biol., vol. 33, pp. R343-R348, 2023. [Link]
A. Narunsky, Kavita, K., Panchapakesan, S. S. S., Fris, M. E., and Breaker, R. R., “A conserved uORF in the ilvBNC mRNA of Corynebacterium species regulates ilv operon expression”, Microb. Genom., vol. 9, 2023. [Link]
H. Sadeeshkumar, Balaji, A., Sutherland, A. G., Mootien, S., Anthony, K. G., and Breaker, R. R., “Screening for small molecule inhibitors of SAH nucleosidase using an SAH riboswitch”, Anal. Biochem, 2023. [Link]
M. G. Mohsen, Midy, M. K., Balaji, A., and Breaker, R. R., “Exploiting natural riboswitches for aptamer engineering and validation”, Nucleic Acids Res., vol. 51, no. 2, pp. 966–981, 2023. [Link]

2022

S. E. Lyon, Harris, K. A., Odzer, N. B., Wilkins, S. G., and Breaker, R. R., “Ornate, large, extremophilic (OLE) RNA forms a kink turn necessary for OapC protein recognition and RNA function”, J. Biol. Chem., vol. 298, no. 12, 2022. [Link]
N. A. White, Sadeeshkumar, H., Sun, A., Sudarsan, N., and Breaker, R. R., “Lithium-sensing riboswitch classes regulate expression of bacterial cation transporter genes”, Sci. Rep., vol. 12, no. 1, 2022. [Link]
M. E. Sherlock, Higgs, G., Yu, D., Widner, D. L., White, N. A., Sudarsan, N., Sadeeshkumar, H., Perkins, K. R., Arachchilage, G. Mirihana, Malkowski, S. N., King, C. G., Harris, K. A., Gaffield, G., Atilho, R. M., and Breaker, R. R., “Architectures and complex functions of tandem riboswitches”, RNA Biol., vol. 19, pp. 1059-1076, 2022. [Link]
K. Kavita and Breaker, R. R., “Discovering riboswitches: the past and the future”, Trends Biochem Sci, 2022. [Link]
N. A. White, Sadeeshkumar, H., Sun, A., Sudarsan, N., and Breaker, R. R., “Na+ riboswitches regulate genes for diverse physiological processes in bacteria”, Nat. Chem. Biol., vol. 18, 2022. [Link]
S. Dhakal, Panchapakesan, S. S. S., Slattery, P., and Breaker, R. R., “Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2′-deoxyguanosine”, PNAS, 2022. [Link]
R. R. Breaker, “The Biochemical Landscape of Riboswitch Ligands”, Biochemistry, vol. 61, 2022. [Link]

2021

A. Roth, Weinberg, Z., Vanderschuren, K., Murdock, M. H., and Breaker, R. R., “Natural circularly permuted group II introns in bacteria produce RNA circles”, iScience, vol. 24, no. 12, 2021. [Link]
X. Portillo, Huang, Y. - T., Breaker, R. R., Horning, D. P., and Joyce, G. F., “Witnessing the structural evolution of an RNA enzyme”, Elife, vol. 10, p. e71557, 2021. [Link]
A. Roth and Breaker, R. R., “Ribozyme Discovery in Bacteria”, Ribozymes, vol. 1, pp. 281-302, 2021. [Link]
K. I. Brewer, Gaffield, G. J., Puri, M., and Breaker, R. R., “DIMPL: a bioinformatics pipeline for the discovery of structured noncoding RNA motifs in bacteria”, Bioinformatics, 2021. [Link]
K. I. Brewer, Greenlee, E. B., Higgs, G., Yu, D., G Arachchilage, M., Chen, X., King, N., White, N., and Breaker, R. R., “Comprehensive discovery of novel structured noncoding RNAs in 26 bacterial genomes”, RNA Biol, 2021. [Link]
Y. Yang, Harris, K. A., Widner, D., and Breaker, R. R., “Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex”, Proc Natl Acad Sci U S A, vol. 118(9), 2021. [Link]
S. S. S. Panchapakesan and Breaker, R. R., “The case of the missing allosteric ribozymes”, Nat Chem Biol, 2021. [Link]

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