2006

R. R. Breaker, “Genetic control by riboswitches and ribozymes”, Faseb Journal, vol. 20, no. 4, 2006.

2005

K. J Wickiser, Cheah, M. T., Breaker, R. R., and Crothers, D. M., “The kinetics of ligand binding by an adenine-sensing riboswitch.”, Biochemistry, vol. 44, no. 40, pp. 13404-14, 2005. [PubMed]
R. Penchovsky and Breaker, R. R., “Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes.”, Nat Biotechnol, vol. 23, no. 11, pp. 1424-33, 2005. [PubMed]
J. E. Barrick, Sudarsan, N., Weinberg, Z., Ruzzo, W. L., and Breaker, R. R., “6S RNA is a widespread regulator of eubacterial RNA polymerase that resembles an open promoter.”, RNA, vol. 11, no. 5, pp. 774-84, 2005. [PubMed]
B. J. Tucker and Breaker, R. R., “Riboswitches as versatile gene control elements.”, Curr Opin Struct Biol, vol. 15, no. 3, pp. 342-8, 2005. [PubMed]
N. Sudarsan, Cohen-Chalamish, S., Nakamura, S., Emilsson, G. Mitchell, and Breaker, R. R., “Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine.”, Chem Biol, vol. 12, no. 12, pp. 1325-35, 2005. [PubMed]
K. J Wickiser, Winkler, W. C., Breaker, R. R., and Crothers, D. M., “The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch.”, Mol Cell, vol. 18, no. 1, pp. 49-60, 2005. [PubMed]
M. Zivarts, Liu, Y., and Breaker, R. R., “Engineered allosteric ribozymes that respond to specific divalent metal ions.”, Nucleic Acids Res, vol. 33, no. 2, pp. 622-31, 2005. [PubMed]
K. A. Corbino, Barrick, J. E., Lim, J., Welz, R., Tucker, B. J., Puskarz, I., Mandal, M., Rudnick, N. D., and Breaker, R. R., “Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.”, Genome Biol, vol. 6, no. 8, p. R70, 2005. [PubMed]
W. C. Winkler and Breaker, R. R., “Regulation of bacterial gene expression by riboswitches.”, Annu Rev Microbiol, vol. 59, pp. 487-517, 2005. [PubMed]
R. R. Breaker, “Gene expression control - Harnessing RNA switches”, Gene Therapy, vol. 12, no. 9, 2005.

2004

M. Mandal, Lee, M., Barrick, J. E., Weinberg, Z., Emilsson, G. Mitchell, Ruzzo, W. L., and Breaker, R. R., “A glycine-dependent riboswitch that uses cooperative binding to control gene expression.”, Science, vol. 306, no. 5694, pp. 275-9, 2004. [PubMed]
A. Sreedhara, Li, Y., and Breaker, R. R., “Ligating DNA with DNA.”, J Am Chem Soc, vol. 126, no. 11, pp. 3454-60, 2004. [PubMed]
W. C. Winkler, Nahvi, A., Roth, A., Collins, J. A., and Breaker, R. R., “Control of gene expression by a natural metabolite-responsive ribozyme.”, Nature, vol. 428, no. 6980, pp. 281-6, 2004. [PubMed]
M. Mandal and Breaker, R. R., “Gene regulation by riboswitches.”, Nat Rev Mol Cell Biol, vol. 5, no. 6, pp. 451-63, 2004. [PubMed]
M. Mandal and Breaker, R. R., “Adenine riboswitches and gene activation by disruption of a transcription terminator.”, Nat Struct Mol Biol, vol. 11, no. 1, pp. 29-35, 2004. [PubMed]
R. R. Breaker, “Natural and engineered nucleic acids as tools to explore biology.”, Nature, vol. 432, no. 7019, pp. 838-45, 2004. [PubMed]
A. Serganov, Yuan, Y. - R., Pikovskaya, O., Polonskaia, A., Malinina, L., Phan, A. Tuân, Hobartner, C., Micura, R., Breaker, R. R., and Patel, D. J., “Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.”, Chem Biol, vol. 11, no. 12, pp. 1729-41, 2004. [PubMed]
J. E. Barrick, Corbino, K. A., Winkler, W. C., Nahvi, A., Mandal, M., Collins, J., Lee, M., Roth, A., Sudarsan, N., Jona, I., J Wickiser, K., and Breaker, R. R., “New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.”, Proc Natl Acad Sci U S A, vol. 101, no. 17, pp. 6421-6, 2004. [PubMed]
A. Nahvi, Barrick, J. E., and Breaker, R. R., “Coenzyme B12 riboswitches are widespread genetic control elements in prokaryotes.”, Nucleic Acids Res, vol. 32, no. 1, pp. 143-50, 2004. [PubMed]

Pages